Several studies have identified specific commensal bacteria in the gut microbiome that are associated with energy levels.

 

Commensal and keystone bacteria influence energy metabolism through various mechanisms, including the production of short-chain fatty acids (SCFAs), modulation of inflammation, and the synthesis of essential vitamins and nutrients.

 

Additionally, dysbiosis can trigger chronic low grade inflammation by allowing harmful bacteria or their by-products, like lipopolysaccharides (LPS), to leak through a compromised gut barrier—a condition known as "leaky gut." This low-grade inflammation increases the body's energy demands and disrupts mitochondrial function which is responsible for energy production.

 

Dysbiosis may also alter hormone signalling, such as insulin or cortisol, further dysregulating energy balance. Over time, these effects—reduced nutrient processing, heightened inflammation, and metabolic disruption which can manifest as persistent low energy.

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